| Variant | Engine | Drivetrain | Transmission | City | Highway | Combined | EV Range | Est. Annual Fuel Cost |
| CLS450 4matic Hybrid | 3L 6-Cyl | 4-Wheel Drive | Automatic 9-spd | 22 MPG | 30 MPG | 25 MPG | — | $3,050 / yr |
Data Boundary Note: EPA specifications are shown by certified vehicle configuration. NHTSA complaints and recall totals are recorded at the model-year level across all configurations.
| Tested Drivetrain / Cab Variant | Overall Rating | Frontal Crash | Side Crash | Rollover Rating | Rollover Risk |
| -Class 4 DR 4WD | Not Rated | Not Rated | Not Rated | Not Rated | — |
| -Class 4 DR RWD | Not Rated | Not Rated | Not Rated | Not Rated | — |
Active Driver Assistance Systems (NHTSA Recorded): Forward Collision Warning (FCW) is documented as Standard and Lane Departure Warning (LDW) is documented as No in official NHTSA records for tested 2022 Mercedes-Benz CLS models.
View complete 2022 Mercedes-Benz CLS crash test & safety breakdown →
Top Reported Problem Categories
Ranked by total consumer complaint submissions recorded by NHTSA
Data Attribution & Context: Complaints are self-reported by vehicle owners to NHTSA and represent unverified consumer submissions. Complaint volume does not equal a statistically controlled failure rate and is not adjusted for total vehicles sold or cumulative mileage driven.
View all 2022 Mercedes-Benz CLS problems & component breakdown (3 categories) →
Affected Component: ELECTRICAL SYSTEM:WIRING
Defect Summary: Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2023 CLS450, E450, E450 All-Terrain, AMG E53, AMG GT43, AMG GT53, and 2021 AMG CLS53 vehicles. The 48-volt ground cable connection located in the engine compartment may not be tightened properly and may result in the ground cable overheating.
Free Manufacturer Remedy: Dealers will inspect the 48-volt ground cable connection and repair it as necessary, free of charge. Owner notification letters were mailed March 22, 2024. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2024MMNNNN.
Affected Component: FUEL SYSTEM, GASOLINE:DELIVERY:FUEL PUMP
Defect Summary: Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2023 C-Class, E-Class, S-Class, CLS, SL, GT, GLC, GLE, GLS, and G-Class vehicles. Please refer to MBUSA's recall report for specific vehicle details. The fuel pump may shutdown, which can result in a loss of drive power.
Free Manufacturer Remedy: Dealers will replace the fuel pump, free of charge. Owner notification letters were mailed on June 14, 2024. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2023070012.
Affected Component: ELECTRICAL SYSTEM:12V/24V/48V BATTERY
Defect Summary: Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2019-2022 CLS450 Coupe and AMG E53, 2019-2021 AMG CLS53 Coupe, and 2021-2022 E450 vehicles. The 12-Volt battery in the trunk may not be properly secured, which, in the event of a crash, can cause electrical connection failure, disabling various safety features including, emergency call (eCall) system, electric seat adjustment, hazard warning lights, and automatic door locks.
Free Manufacturer Remedy: Dealers will secure the 12V battery, free of charge. Owner notification letters were mailed January 20, 2023. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2022100009.
View all 2022 Mercedes-Benz CLS recalls & campaign history (6 campaigns) →