2021 Mercedes-Benz C-Class EPA Fuel Economy Summary

The 2021 Mercedes-Benz C-Class delivers an EPA-certified 20–27 MPG combined (17–24 city / 25–35 highway depending on engine and drivetrain) across 18 configurations. Estimated annual fuel costs range from $2,800 to $3,800.

Combined MPG
20–27 MPG
55% city / 45% highway weighted
City MPG
17–24 MPG
Stop-and-go urban cycle
Highway MPG
25–35 MPG
Sustained open-highway test
Annual Fuel Cost
$2,800–3,800
EPA estimate @ 15,000 miles/yr

Official EPA Fuel Economy Ratings by Configuration (18 Variants)

Laboratory certification test values across engine, transmission, and drivetrain permutations

Configuration / Model Powertrain Drivetrain Transmission City Highway Combined Annual Fuel Cost CO2 (g/mi)
C300 Coupe Premium 2L 4-Cyl Gas Rear-Wheel Drive Automatic 9-spd 24 MPG 33 MPG 27 MPG $2,800 —
C300 4matic Premium 2L 4-Cyl Gas 4-Wheel Drive Automatic 9-spd 23 MPG 33 MPG 27 MPG $2,800 —
C300 Premium 2L 4-Cyl Gas Rear-Wheel Drive Automatic 9-spd 23 MPG 35 MPG 27 MPG $2,800 —
C300 4matic Coupe Premium 2L 4-Cyl Gas 4-Wheel Drive Automatic 9-spd 23 MPG 32 MPG 26 MPG $2,900 —
C300 Convertible Premium 2L 4-Cyl Gas Rear-Wheel Drive Automatic 9-spd 23 MPG 31 MPG 26 MPG $2,900 —
GLC300 Premium 2L 4-Cyl Gas Rear-Wheel Drive Automatic 9-spd 22 MPG 29 MPG 25 MPG $3,050 —
C300 4matic Convertible Premium 2L 4-Cyl Gas 4-Wheel Drive Automatic 9-spd 22 MPG 30 MPG 25 MPG $3,050 —
GLC300 4matic Coupe Premium 2L 4-Cyl Gas 4-Wheel Drive Automatic 9-spd 22 MPG 28 MPG 24 MPG $3,150 —
GLC300 4matic Premium 2L 4-Cyl Gas 4-Wheel Drive Automatic 9-spd 21 MPG 28 MPG 23 MPG $3,300 —
AMG C43 4matic Coupe Premium 3L 6-Cyl Gas 4-Wheel Drive Automatic 9-spd 19 MPG 27 MPG 22 MPG $3,450 —
AMG C43 4matic Convertible Premium 3L 6-Cyl Gas 4-Wheel Drive Automatic 9-spd 19 MPG 27 MPG 22 MPG $3,450 —
AMG C63 Premium 4L 8-Cyl Gas Rear-Wheel Drive Automatic 9-spd 17 MPG 26 MPG 21 MPG $3,600 —
AMG C63 S Premium 4L 8-Cyl Gas Rear-Wheel Drive Automatic 9-spd 17 MPG 26 MPG 21 MPG $3,600 —
AMG C43 4matic Premium 3L 6-Cyl Gas 4-Wheel Drive Automatic 9-spd 18 MPG 27 MPG 21 MPG $3,600 —
AMG C63 S Convertible Premium 4L 8-Cyl Gas Rear-Wheel Drive Automatic 9-spd 17 MPG 25 MPG 20 MPG $3,800 —
AMG C63 Convertible Premium 4L 8-Cyl Gas Rear-Wheel Drive Automatic 9-spd 17 MPG 25 MPG 20 MPG $3,800 —
AMG C63 S Coupe Premium 4L 8-Cyl Gas Rear-Wheel Drive Automatic 9-spd 17 MPG 26 MPG 20 MPG $3,800 —
AMG C63 Coupe Premium 4L 8-Cyl Gas Rear-Wheel Drive Automatic 9-spd 17 MPG 26 MPG 20 MPG $3,800 —
EPA Test Methodology: Fuel economy estimates are determined by vehicle manufacturers in accordance with EPA regulations (40 CFR Part 600) and verified by EPA laboratories. Estimates assume 15,000 miles per year of driving (55% city, 45% highway) at prevailing fuel and electricity prices.

Deterministic Fuel Cost & Consumption Benchmarks

Standardized annual energy consumption and operating cost metrics based on 15,000 annual miles

Fuel Cost per 25 Miles

$3.24–$4.38

Based on $3.50 per gallon regular gasoline

Annual Fuel Consumption

556–750 Gallons

Estimated annual energy units needed for 15,000 miles

5-Year Fuel Cost vs Avg Vehicle

Official EPA Benchmark

Compared to the average new vehicle over 5 years

Related Official Reports for 2021 Mercedes-Benz C-Class

Cross-reference safety ratings, owner defect complaints, and recall campaigns

Official US Government Data Provenance

Fuel economy ratings, electric range figures, and energy cost estimates on this page are retrieved directly from the United States Environmental Protection Agency (EPA) and U.S. Department of Energy (FuelEconomy.gov) certified vehicle database.

Local Production Store Compiled: August 2026 • Deterministic Audited Dataset • Zero Dynamic External API Runtime Latency.