2015 Mercedes-Benz E-Class EPA Fuel Economy Summary

The 2015 Mercedes-Benz E-Class delivers an EPA-certified 20–25 MPG combined (17–24 city / 25–29 highway depending on engine and drivetrain) across 16 configurations. Hybrid variants achieve up to 25 MPG combined, compared to 23 MPG for standard gasoline trims. Estimated annual fuel costs range from $3,050 to $3,800.

Combined MPG
20–25 MPG
55% city / 45% highway weighted
City MPG
17–24 MPG
Stop-and-go urban cycle
Highway MPG
25–29 MPG
Sustained open-highway test
Annual Fuel Cost
$3,050–3,800
EPA estimate @ 15,000 miles/yr

2015 Mercedes-Benz E-Class Powertrain & Efficiency Comparison

Factual efficiency differences across gasoline, hybrid, plug-in hybrid, and electric variants

Internal Combustion

Standard Gasoline Trims

20–23 MPG Combined

Annual Fuel Cost: $3,300–$3,800 (15 configurations)

Gas-Electric Hybrid

Hybrid (HEV) Trims

25–25 MPG Combined

Annual Fuel Cost: $3,050–$3,050 (Saves ~$250/yr vs gas)

Official EPA Fuel Economy Ratings by Configuration (16 Variants)

Laboratory certification test values across engine, transmission, and drivetrain permutations

Configuration / Model Powertrain Drivetrain Transmission City Highway Combined Annual Fuel Cost CO2 (g/mi)
E400 Hybrid Premium 3.5L Hybrid Rear-Wheel Drive Automatic 7-spd 24 MPG 28 MPG 25 MPG $3,050 —
E350 Convertible Premium 3.5L 6-Cyl Gas Rear-Wheel Drive Automatic 7-spd 20 MPG 28 MPG 23 MPG $3,300 —
E350 Premium 3.5L 6-Cyl Gas Rear-Wheel Drive Automatic 7-spd 20 MPG 28 MPG 23 MPG $3,300 —
E350 4matic Premium 3.5L 6-Cyl Gas 4-Wheel Drive Automatic 7-spd 20 MPG 27 MPG 23 MPG $3,300 —
E350 Premium or E85 3.5L 6-Cyl Gas Rear-Wheel Drive Automatic 7-spd 20 MPG 28 MPG 23 MPG $3,300 —
E350 4matic Premium or E85 3.5L 6-Cyl Gas 4-Wheel Drive Automatic 7-spd 20 MPG 27 MPG 23 MPG $3,300 —
E400 Premium 3L 6-Cyl Gas Rear-Wheel Drive Automatic 7-spd 20 MPG 29 MPG 23 MPG $3,300 —
E400 Coupe Premium 3L 6-Cyl Gas Rear-Wheel Drive Automatic 7-spd 20 MPG 29 MPG 23 MPG $3,300 —
E400 4matic Coupe Premium 3L 6-Cyl Gas 4-Wheel Drive Automatic 7-spd 20 MPG 28 MPG 23 MPG $3,300 —
E400 Convertible Premium 3L 6-Cyl Gas Rear-Wheel Drive Automatic 7-spd 20 MPG 29 MPG 23 MPG $3,300 —
E350 Coupe Premium 3.5L 6-Cyl Gas Rear-Wheel Drive Automatic 7-spd 19 MPG 28 MPG 22 MPG $3,450 —
E350 4matic (wagon) Premium 3.5L 6-Cyl Gas 4-Wheel Drive Automatic 7-spd 20 MPG 26 MPG 22 MPG $3,450 —
E400 4matic Premium 3L 6-Cyl Gas 4-Wheel Drive Automatic 7-spd 20 MPG 27 MPG 22 MPG $3,450 —
E400 4matic (station wagon) Premium 3L 6-Cyl Gas 4-Wheel Drive Automatic 7-spd 19 MPG 26 MPG 22 MPG $3,450 —
E550 Coupe Premium 4.7L 8-Cyl Gas Rear-Wheel Drive Automatic 7-spd 18 MPG 26 MPG 21 MPG $3,600 —
E550 Convertible Premium 4.7L 8-Cyl Gas Rear-Wheel Drive Automatic 7-spd 17 MPG 25 MPG 20 MPG $3,800 —
EPA Test Methodology: Fuel economy estimates are determined by vehicle manufacturers in accordance with EPA regulations (40 CFR Part 600) and verified by EPA laboratories. Estimates assume 15,000 miles per year of driving (55% city, 45% highway) at prevailing fuel and electricity prices.

Deterministic Fuel Cost & Consumption Benchmarks

Standardized annual energy consumption and operating cost metrics based on 15,000 annual miles

Fuel Cost per 25 Miles

$3.50–$4.38

Based on $3.50 per gallon regular gasoline

Annual Fuel Consumption

600–750 Gallons

Estimated annual energy units needed for 15,000 miles

5-Year Fuel Cost vs Avg Vehicle

Official EPA Benchmark

Compared to the average new vehicle over 5 years

Related Official Reports for 2015 Mercedes-Benz E-Class

Cross-reference safety ratings, owner defect complaints, and recall campaigns

Official US Government Data Provenance

Fuel economy ratings, electric range figures, and energy cost estimates on this page are retrieved directly from the United States Environmental Protection Agency (EPA) and U.S. Department of Energy (FuelEconomy.gov) certified vehicle database.

Local Production Store Compiled: August 2026 • Deterministic Audited Dataset • Zero Dynamic External API Runtime Latency.