2017 Mercedes-Benz S-Class EPA Fuel Economy Summary

The 2017 Mercedes-Benz S-Class delivers an EPA-certified 16–21 MPG combined (13–18 city / 18–26 highway depending on engine and drivetrain) across 17 configurations. Plug-in hybrid (PHEV) models offer up to 14 miles of all-electric range at 58 MPGe. Estimated annual fuel costs range from $2,900 to $4,750.

Combined MPG
16–21 MPG
55% city / 45% highway weighted
City MPG
13–18 MPG
Stop-and-go urban cycle
Highway MPG
18–26 MPG
Sustained open-highway test
Annual Fuel Cost
$2,900–4,750
EPA estimate @ 15,000 miles/yr

2017 Mercedes-Benz S-Class Powertrain & Efficiency Comparison

Factual efficiency differences across gasoline, hybrid, plug-in hybrid, and electric variants

Internal Combustion

Standard Gasoline Trims

16–21 MPG Combined

Annual Fuel Cost: $3,600–$4,750 (16 configurations)

Plug-In Hybrid

Plug-In Hybrid (PHEV)

14 mi EV Range • 58 MPGe

Gasoline Combined: 26 MPG • Annual Energy Cost: $2,900

Official EPA Fuel Economy Ratings by Configuration (17 Variants)

Laboratory certification test values across engine, transmission, and drivetrain permutations

Configuration / Model Powertrain Drivetrain Transmission City Highway Combined EV Range Annual Fuel Cost CO2 (g/mi)
S550e Premium and Electricity 3L Plug-in Hybrid Rear-Wheel Drive Automatic 7-spd 54 MPGe (24 MPG) 63 MPGe (30 MPG) 58 MPGe (26 MPG) 14 mi $2,900
CLS550 Premium 4.7L 8-Cyl Gas Rear-Wheel Drive Automatic 9-spd 18 MPG 26 MPG 21 MPG $3,600
S550 Premium 4.7L 8-Cyl Gas Rear-Wheel Drive Automatic 9-spd 18 MPG 26 MPG 21 MPG $3,600
S550 Convertible Premium 4.7L 8-Cyl Gas Rear-Wheel Drive Automatic 9-spd 17 MPG 25 MPG 20 MPG $3,800
CLS550 4matic Premium 4.7L 8-Cyl Gas 4-Wheel Drive Automatic 9-spd 17 MPG 25 MPG 20 MPG $3,800
S550 4matic Premium 4.7L 8-Cyl Gas 4-Wheel Drive Automatic 9-spd 16 MPG 25 MPG 20 MPG $3,800
S550 4matic Coupe Premium 4.7L 8-Cyl Gas 4-Wheel Drive Automatic 9-spd 17 MPG 25 MPG 20 MPG $3,800
GLS450 4matic Premium 3L 6-Cyl Gas 4-Wheel Drive Automatic 9-spd 17 MPG 22 MPG 19 MPG $4,000
Maybach S550 4matic Premium 4.7L 8-Cyl Gas 4-Wheel Drive Automatic 9-spd 16 MPG 24 MPG 19 MPG $4,000
AMG S63 4matic Coupe Premium 5.5L 8-Cyl Gas 4-Wheel Drive Automatic 7-spd 15 MPG 23 MPG 18 MPG $4,200
AMG S63 4matic Premium 5.5L 8-Cyl Gas 4-Wheel Drive Automatic 7-spd 15 MPG 23 MPG 18 MPG $4,200
AMG S63 4matic Convertible Premium 5.5L 8-Cyl Gas 4-Wheel Drive Automatic 7-spd 14 MPG 22 MPG 17 MPG $4,450
GLS550 4matic Premium 4.7L 8-Cyl Gas 4-Wheel Drive Automatic 9-spd 14 MPG 18 MPG 16 MPG $4,750
Maybach S600 Premium 6L 12-Cyl Gas Rear-Wheel Drive Automatic 7-spd 13 MPG 21 MPG 16 MPG $4,750
S600 Premium 6L 12-Cyl Gas Rear-Wheel Drive Automatic 7-spd 13 MPG 22 MPG 16 MPG $4,750
AMG S65 Premium 6L 12-Cyl Gas Rear-Wheel Drive Automatic 7-spd 13 MPG 22 MPG 16 MPG $4,750
Maybach S650 Convertible Premium 6L 12-Cyl Gas Rear-Wheel Drive Automatic 7-spd 13 MPG 21 MPG 16 MPG $4,750
EPA Test Methodology: Fuel economy estimates are determined by vehicle manufacturers in accordance with EPA regulations (40 CFR Part 600) and verified by EPA laboratories. Estimates assume 15,000 miles per year of driving (55% city, 45% highway) at prevailing fuel and electricity prices.

Deterministic Fuel Cost & Consumption Benchmarks

Standardized annual energy consumption and operating cost metrics based on 15,000 annual miles

Fuel Cost per 25 Miles

$4.17–$5.47

Based on $3.50 per gallon regular gasoline

Annual Fuel Consumption

714–938 Gallons

Estimated annual energy units needed for 15,000 miles

5-Year Fuel Cost vs Avg Vehicle

Official EPA Benchmark

Compared to the average new vehicle over 5 years

Official US Government Data Provenance

Fuel economy ratings, electric range figures, and energy cost estimates on this page are retrieved directly from the United States Environmental Protection Agency (EPA) and U.S. Department of Energy (FuelEconomy.gov) certified vehicle database.

Local Production Store Compiled: August 2026 • Deterministic Audited Dataset • Zero Dynamic External API Runtime Latency.