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Combined MPG
16–22 MPG
55% city / 45% highway weighted
City Driving Rating
13–19 MPG
Stop-and-go urban cycle
Highway Driving Rating
19–28 MPG
Sustained open-highway test
Annual Fuel Cost
$3,450–4,750
EPA estimate @ 15,000 miles/yr
Laboratory Fuel Economy Certification

Executive Efficiency Findings

The 2018 Mercedes-Benz S-Class delivers an EPA-certified 16–22 MPG combined across 18 configurations. Estimated annual fuel costs range from $3,450 to $4,750.

EPA Testing Standards: Ratings derived from official dynamometer laboratory tests under 40 CFR Part 600. Real-world fuel economy varies based on driving style, ambient temperature, cargo payload, and terrain.
Certified Powertrain Attributes
  • • Certified Configurations: 18 trim and powertrain permutation(s).
  • • Combined Rating Range: 16–22 MPG.
  • • Annual Energy Cost: $3,450–4,750 (15k mi/yr).
Certified Ratings Matrix

Official EPA Fuel Economy Ratings by Configuration (18)

Laboratory certification test values across engine, transmission, and drivetrain permutations

Configuration / Model Powertrain Drivetrain Transmission City Highway Combined Annual Fuel Cost CO2 (g/mi)
S450 Premium 3L 6-Cyl Gas Rear-Wheel Drive Automatic 9-spd 19 MPG 28 MPG 22 MPG $3,450 —
S450 4matic Premium 3L 6-Cyl Gas 4-Wheel Drive Automatic 9-spd 18 MPG 28 MPG 22 MPG $3,450 —
S560 4matic Premium 4L 8-Cyl Gas 4-Wheel Drive Automatic 9-spd 17 MPG 27 MPG 21 MPG $3,600 —
CLS550 Premium 4.7L 8-Cyl Gas Rear-Wheel Drive Automatic 9-spd 18 MPG 26 MPG 21 MPG $3,600 —
S560 4matic Coupe Premium 4L 8-Cyl Gas 4-Wheel Drive Automatic 9-spd 17 MPG 27 MPG 21 MPG $3,600 —
S560 Premium 4L 8-Cyl Gas Front-Wheel Drive Automatic 9-spd 17 MPG 27 MPG 21 MPG $3,600 —
AMG S63 4matic Premium 4L 8-Cyl Gas 4-Wheel Drive Automatic 9-spd 17 MPG 26 MPG 20 MPG $3,800 —
CLS550 4matic Premium 4.7L 8-Cyl Gas 4-Wheel Drive Automatic 9-spd 17 MPG 25 MPG 20 MPG $3,800 —
S560 Convertible Premium 4L 8-Cyl Gas Front-Wheel Drive Automatic 9-spd 17 MPG 26 MPG 20 MPG $3,800 —
AMG S63 4matic Coupe Premium 4L 8-Cyl Gas 4-Wheel Drive Automatic 9-spd 17 MPG 27 MPG 20 MPG $3,800 —
GLS450 4matic Premium 3L 6-Cyl Gas 4-Wheel Drive Automatic 9-spd 17 MPG 22 MPG 19 MPG $4,000 —
Maybach S560 4matic Premium 4L 8-Cyl Gas 4-Wheel Drive Automatic 9-spd 16 MPG 25 MPG 19 MPG $4,000 —
AMG S63 4matic Convertible Premium 4L 8-Cyl Gas 4-Wheel Drive Automatic 9-spd 15 MPG 24 MPG 18 MPG $4,200 —
GLS550 4matic Premium 4.7L 8-Cyl Gas 4-Wheel Drive Automatic 9-spd 14 MPG 19 MPG 16 MPG $4,750 —
Maybach S650 Premium 6L 12-Cyl Gas Rear-Wheel Drive Automatic 7-spd 13 MPG 21 MPG 16 MPG $4,750 —
AMG S65 Premium 6L 12-Cyl Gas Rear-Wheel Drive Automatic 7-spd 13 MPG 22 MPG 16 MPG $4,750 —
AMG S65 Convertible Premium 6L 12-Cyl Gas Rear-Wheel Drive Automatic 7-spd 14 MPG 21 MPG 16 MPG $4,750 —
AMG S65 Coupe Premium 6L 12-Cyl Gas Rear-Wheel Drive Automatic 7-spd 13 MPG 21 MPG 16 MPG $4,750 —
Operating Cost Economics

Standardized Energy Cost & Consumption Benchmarks

Standardized annual energy consumption and operating cost metrics based on 15,000 annual miles

ENERGY UNIT 25 MI

Fuel Cost per 25 Miles

$3.98–$5.47

Based on $3.50 per gallon regular gasoline

ANNUAL TOTAL 15K MI

Annual Fuel Consumption

682–938 Gal

Estimated annual energy units needed for 15,000 miles

5-YEAR VALUE SAVINGS

5-Year Fuel Cost vs Avg Vehicle

EPA Benchmark

Compared to the average new vehicle over 5 years

Related Workstations

Related Official Reports for 2018 Mercedes-Benz S-Class

Cross-reference safety ratings, owner defect complaints, and recall campaigns

← 2018 Mercedes-Benz S-Class Overview

Vehicle summary, specifications, and primary KPI metrics.

2018 Mercedes-Benz S-Class Safety Ratings →

NHTSA 5-Star NCAP crash tests, rollover risk, and active driver assistance.

2018 Mercedes-Benz S-Class Owner Complaints (29) →

NHTSA consumer defect complaint filings by affected component.

2018 Mercedes-Benz S-Class Safety Recalls (12) →

Official safety recall notices, defects, and free repair instructions.
Search Intelligence

Quick Answers: EPA Fuel Economy, Electric Range & Energy Costs for the 2018 Mercedes-Benz S-Class

Direct, deterministic answers synthesized from verified United States government databases for the 2018 Mercedes-Benz S-Class

What gas mileage (MPG) does the 2018 Mercedes-Benz S-Class get?

The 2018 Mercedes-Benz S-Class achieves an EPA-certified rating of 16 to 22 MPG combined across 18 certified configuration(s).

City ratings range from 13 to 19 MPG, and highway ratings range from 19 to 28 MPG.

Source: EPA FuelEconomy.gov (40 CFR Part 600)

What is the estimated annual fuel or energy cost for the 2018 Mercedes-Benz S-Class?

Using AutoUtility's standardized operating cost model, estimated annual fueling and energy costs range between $3,450 and $4,750 for the 2018 Mercedes-Benz S-Class.

Calculated under AutoUtility's standardized methodology (15,000 miles per year, 55% city / 45% highway driving, $3.50/gallon regular gasoline, $0.16/kWh electricity) using official EPA dynamometer consumption ratings.

Source: AutoUtility Operating Cost Model (EPA-Certified Baseline)
Official US Government Data Provenance

Fuel economy ratings, electric range figures, and energy cost estimates on this page are retrieved directly from the United States Environmental Protection Agency (EPA) and U.S. Department of Energy (FuelEconomy.gov) certified vehicle database under 40 CFR Part 600.

Local Production Store Compiled: August 2026 • Deterministic Audited Dataset • Zero Dynamic External API Runtime Latency.