2018 Mercedes-Benz S-Class Specifications Overview

The 2018 Mercedes-Benz S-Class is certified across 18 configurations with 3L 6-Cylinder Engine, 4L 8-Cylinder Engine, 4.7L 8-Cylinder Engine, 6L 12-Cylinder Engine powertrain options. Available drivetrain layouts include Rear-Wheel Drive, 4-Wheel Drive, Front-Wheel Drive paired with Automatic 9-spd or Automatic 7-spd. EPA classified under the Large Cars / Compact Cars / Subcompact Cars / Standard Sport Utility Vehicle 4WD size category. Platform architecture belongs to the 6th Generation (W222) vehicle family.

Engine / Motors
4 Options
3L 6-Cylinder Engine, 4L 8-Cylinder Engine...
Drivetrain Options
3 Drivetrains
Rear-Wheel Drive, 4-Wheel Drive, Front-Wheel Drive
Transmissions
2 Options
Automatic 9-spd, Automatic 7-spd
Vehicle Classification
Large Cars
Official EPA regulatory class

Certified Powertrain & Transmission Configurations (18)

Official laboratory certification specifications for each factory engine, transmission, and drivetrain permutation

Configuration / Model Engine & Displacement Cylinders Induction / Tech Transmission Drivetrain Fuel System
S450 Large Cars 3L 6-Cylinder Engine 6 Naturally Aspirated Automatic 9-spd Rear-Wheel Drive Premium
S450 4matic Large Cars 3L 6-Cylinder Engine 6 Naturally Aspirated Automatic 9-spd 4-Wheel Drive Premium
S560 4matic Large Cars 4L 8-Cylinder Engine 8 Naturally Aspirated Automatic 9-spd 4-Wheel Drive Premium
CLS550 Compact Cars 4.7L 8-Cylinder Engine 8 Naturally Aspirated Automatic 9-spd Rear-Wheel Drive Premium
S560 4matic Coupe Compact Cars 4L 8-Cylinder Engine 8 Naturally Aspirated Automatic 9-spd 4-Wheel Drive Premium
S560 Large Cars 4L 8-Cylinder Engine 8 Naturally Aspirated Automatic 9-spd Front-Wheel Drive Premium
AMG S63 4matic Large Cars 4L 8-Cylinder Engine 8 Naturally Aspirated Automatic 9-spd 4-Wheel Drive Premium
CLS550 4matic Compact Cars 4.7L 8-Cylinder Engine 8 Naturally Aspirated Automatic 9-spd 4-Wheel Drive Premium
S560 Convertible Subcompact Cars 4L 8-Cylinder Engine 8 Naturally Aspirated Automatic 9-spd Front-Wheel Drive Premium
AMG S63 4matic Coupe Compact Cars 4L 8-Cylinder Engine 8 Naturally Aspirated Automatic 9-spd 4-Wheel Drive Premium
GLS450 4matic Standard Sport Utility Vehicle 4WD 3L 6-Cylinder Engine 6 Naturally Aspirated Automatic 9-spd 4-Wheel Drive Premium
Maybach S560 4matic Large Cars 4L 8-Cylinder Engine 8 Naturally Aspirated Automatic 9-spd 4-Wheel Drive Premium
AMG S63 4matic Convertible Subcompact Cars 4L 8-Cylinder Engine 8 Naturally Aspirated Automatic 9-spd 4-Wheel Drive Premium
GLS550 4matic Standard Sport Utility Vehicle 4WD 4.7L 8-Cylinder Engine 8 Naturally Aspirated Automatic 9-spd 4-Wheel Drive Premium
Maybach S650 Large Cars 6L 12-Cylinder Engine 12 Naturally Aspirated Automatic 7-spd Rear-Wheel Drive Premium
AMG S65 Large Cars 6L 12-Cylinder Engine 12 Naturally Aspirated Automatic 7-spd Rear-Wheel Drive Premium
AMG S65 Convertible Subcompact Cars 6L 12-Cylinder Engine 12 Naturally Aspirated Automatic 7-spd Rear-Wheel Drive Premium
AMG S65 Coupe Compact Cars 6L 12-Cylinder Engine 12 Naturally Aspirated Automatic 7-spd Rear-Wheel Drive Premium
EPA Certification Standards: Powertrain and transmission specifications represent official laboratory configuration records filed under 40 CFR Part 600. For detailed fuel economy ratings, electric range, and annual fuel costs, explore the 2018 Mercedes-Benz S-Class MPG & Range Report.

Regulatory Classification & Safety Architecture

Federal classification standards and standard active driver assistance system capabilities

EPA Regulatory Size Class

  • Large Cars
  • Compact Cars
  • Subcompact Cars
  • Standard Sport Utility Vehicle 4WD

NHTSA NCAP Body Formats

  • 2018 Mercedes-Benz S-Class Coupe 2 DR 2WD
  • 2018 Mercedes-Benz S-Class C 4WD
  • 2018 Mercedes-Benz S-Class 4 DR 4WD
  • 2018 Mercedes-Benz S-Class Coupe 2 DR 4WD
  • 2018 Mercedes-Benz S-Class C RWD
  • 2018 Mercedes-Benz S-Class 4 DR RWD

Active Safety Technology

Evaluated under federal safety compliance standards.

Related Official Reports for 2018 Mercedes-Benz S-Class

Cross-reference fuel economy, safety ratings, owner defect complaints, and recall notices

Official US Government Data Provenance

Powertrain, transmission, drivetrain, and regulatory classification specifications on this page are derived directly from the United States Environmental Protection Agency (EPA) and National Highway Traffic Safety Administration (NHTSA) official laboratory certification registries.

Local Production Store Compiled: August 2026 • Deterministic Audited Dataset • Zero Dynamic External API Runtime Latency.