2023 Mercedes-Benz S-Class EPA Fuel Economy Summary

The 2023 Mercedes-Benz S-Class delivers an EPA-certified 14–25 MPG combined (12–22 city / 20–30 highway depending on engine and drivetrain) across 10 configurations. Hybrid variants achieve up to 25 MPG combined, compared to 14 MPG for standard gasoline trims. Plug-in hybrid (PHEV) models offer up to 56 miles of all-electric range at 49 MPGe. Estimated annual fuel costs range from $950 to $5,450.

Combined MPG
14–25 MPG
55% city / 45% highway weighted
City MPG
12–22 MPG
Stop-and-go urban cycle
Highway MPG
20–30 MPG
Sustained open-highway test
Annual Fuel Cost
$950–5,450
EPA estimate @ 15,000 miles/yr

2023 Mercedes-Benz S-Class Powertrain & Efficiency Comparison

Factual efficiency differences across gasoline, hybrid, plug-in hybrid, and electric variants

Internal Combustion

Standard Gasoline Trims

14–14 MPG Combined

Annual Fuel Cost: $5,450–$5,450 (1 configuration)

Gas-Electric Hybrid

Hybrid (HEV) Trims

17–25 MPG Combined

Annual Fuel Cost: $3,050–$4,450 (Saves ~$2,400/yr vs gas)

Plug-In Hybrid

Plug-In Hybrid (PHEV)

56 mi EV Range • 49 MPGe

Gasoline Combined: 23 MPG • Annual Energy Cost: $3,300

All-Electric

Battery Electric (BEV)

285–285 mi Range • 77 MPGe

Annual Energy Cost: $950–$5,450 (1 configuration)

Official EPA Fuel Economy Ratings by Configuration (10 Variants)

Laboratory certification test values across engine, transmission, and drivetrain permutations

Configuration / Model Powertrain Drivetrain Transmission City Highway Combined EV Range Annual Fuel Cost CO2 (g/mi)
EQS 580 4matic (SUV) Electricity Electric (BEV) All-Wheel Drive Automatic (A1) 79 MPGe 74 MPGe 77 MPGe 285 mi $950 —
CLS450 4matic Premium 3L Hybrid All-Wheel Drive Automatic 9-spd 22 MPG 30 MPG 25 MPG — $3,050 —
S580e 4matic Premium and Electricity 3L Plug-in Hybrid All-Wheel Drive Automatic 9-spd 60 MPGe (20 MPG) 35 MPGe (29 MPG) 49 MPGe (23 MPG) 56 mi $3,300 —
S500 4matic Premium 3L Hybrid All-Wheel Drive Automatic 9-spd 20 MPG 28 MPG 23 MPG — $3,300 —
GLS450 4matic Premium 3L Hybrid All-Wheel Drive Automatic 9-spd 18 MPG 23 MPG 20 MPG — $3,800 —
S580 4matic Premium 4L Hybrid All-Wheel Drive Automatic 9-spd 16 MPG 25 MPG 19 MPG — $4,000 —
S580 4matic Maybach Premium 4L Hybrid All-Wheel Drive Automatic 9-spd 15 MPG 25 MPG 18 MPG — $4,200 —
GLS580 4matic Premium 4L Hybrid All-Wheel Drive Automatic 9-spd 16 MPG 21 MPG 18 MPG — $4,200 —
GLS600 4matic Maybach Premium 4L Hybrid All-Wheel Drive Automatic 9-spd 15 MPG 20 MPG 17 MPG — $4,450 —
Maybach S680 4matic Premium 6L 12-Cyl Gas All-Wheel Drive Automatic 9-spd 12 MPG 20 MPG 14 MPG — $5,450 —
EPA Test Methodology: Fuel economy estimates are determined by vehicle manufacturers in accordance with EPA regulations (40 CFR Part 600) and verified by EPA laboratories. Estimates assume 15,000 miles per year of driving (55% city, 45% highway) at prevailing fuel and electricity prices.

Deterministic Fuel Cost & Consumption Benchmarks

Standardized annual energy consumption and operating cost metrics based on 15,000 annual miles

Fuel Cost per 25 Miles

$3.50–$6.25

Based on $3.50 per gallon regular gasoline

Annual Fuel Consumption

600–1071 Gallons

Estimated annual energy units needed for 15,000 miles

5-Year Fuel Cost vs Avg Vehicle

Official EPA Benchmark

Compared to the average new vehicle over 5 years

Related Official Reports for 2023 Mercedes-Benz S-Class

Cross-reference safety ratings, owner defect complaints, and recall campaigns

Official US Government Data Provenance

Fuel economy ratings, electric range figures, and energy cost estimates on this page are retrieved directly from the United States Environmental Protection Agency (EPA) and U.S. Department of Energy (FuelEconomy.gov) certified vehicle database.

Local Production Store Compiled: August 2026 • Deterministic Audited Dataset • Zero Dynamic External API Runtime Latency.