| Variant | Engine | Drivetrain | Transmission | City | Highway | Combined | EV Range | Est. Annual Fuel Cost |
| Sienna Hybrid 2WD Hybrid | 2.5L 4-Cyl | Front-Wheel Drive | Automatic (AV-S6) | 36 MPG | 36 MPG | 36 MPG | — | $1,700 / yr |
| Sienna Hybrid AWD Hybrid | 2.5L 4-Cyl | All-Wheel Drive | Automatic (AV-S6) | 35 MPG | 36 MPG | 35 MPG | — | $1,750 / yr |
Data Boundary Note: EPA specifications are shown by certified vehicle configuration. NHTSA complaints and recall totals are recorded at the model-year level across all configurations.
| Tested Drivetrain / Cab Variant | Overall Rating | Frontal Crash | Side Crash | Rollover Rating | Rollover Risk |
| HYBRID VAN FWD | | | | | 14.000000000000002% |
| HYBRID VAN AWD | | | | | 12.7% |
Active Driver Assistance Systems (NHTSA Recorded): Forward Collision Warning (FCW) is documented as Standard and Lane Departure Warning (LDW) is documented as Standard in official NHTSA records for tested 2021 Toyota Sienna models.
View complete 2021 Toyota Sienna crash test & safety breakdown →
Top Reported Problem Categories
Ranked by total consumer complaint submissions recorded by NHTSA
Data Attribution & Context: Complaints are self-reported by vehicle owners to NHTSA and represent unverified consumer submissions. Complaint volume does not equal a statistically controlled failure rate and is not adjusted for total vehicles sold or cumulative mileage driven.
View all 2021 Toyota Sienna problems & component breakdown (18 categories) →
Affected Component: EQUIPMENT ADAPTIVE/MOBILITY:WHEELCHAIR RESTRAINTS/SECUREMENT:LATCH/ANCHOR:
Defect Summary: Vantage Mobility, LLC (VM) is recalling certain 2021-2026 Honda Odyssey, 2021-2025 Chrysler Pacifica, and Toyota Sienna vehicles equipped with QRT-Deluxe and QRT-Max wheelchair restraints. The retractors may not lock, preventing the wheelchair from being properly secured.
Free Manufacturer Remedy: Dealers will inspect and replace the retractors, free of charge. Owner notification letters was mailed January 27, 2026. Owners may contact Vantage Mobility customer service at 1-800-488-9082.
Affected Component: SEATS:MID/REAR ASSEMBLY:RECLINER
Defect Summary: Toyota Motor Engineering & Manufacturing (Toyota) is recalling certain 2021-2025 Sienna Hybrid vehicles. The bolts for the seatbacks on the third-row seat assemblies may not be tightened properly. As such, these vehicles fail to comply with the requirements of Federal Motor Vehicle Safety Standard (FMVSS) numbers 202, "Head Restraints," 207, "Seating Systems," and 225, "Child Restraint Anchorage Systems."
Free Manufacturer Remedy: Dealers will tighten the seat assembly bolts, free of charge. Owner notification letters were mailed April 1, 2025. Owners may contact Toyota's customer service at 1-800-331-4331. Toyota's number for this recall is 25TA05.
Affected Component: AIR BAGS:SENSOR:OCCUPANT CLASSIFICATION
Defect Summary: Toyota Motor Engineering & Manufacturing (Toyota) is recalling certain 2020-2021 Avalon, Avalon Hybrid, Corolla, Highlander, Highlander Hybrid, RAV4, RAV4 Hybrid, Lexus ES350, Lexus RX350, Lexus RX450H, 2021 Sienna Hybrid, Lexus ES250, 2020-2022 Camry, Camry Hybrid, and ES300H vehicles. A short circuit may develop in the Occupant Classification System (OCS) sensor, preventing the front passenger air bag from deploying.
Free Manufacturer Remedy: Dealers will inspect and replace the sensor as necessary, free of charge. Interim letters notifying owners of the safety risk were mailed in February 2024. Some final remedy owner letters were mailed October 31, 2024. Letters will continue to be mailed in phases through January 2026. Owners may contact Toyota customer service at 1-800-331-4331. Toyota's number for this recall is 23TB15/23TA15 Lexus 23LB03/23LA03.
View all 2021 Toyota Sienna recalls & campaign history (4 campaigns) →
