AutoUtility currently tracks 25 official NHTSA owner defect complaints for the 2021 Mercedes-Benz E-Class. Electrical System issues are the most frequently reported category, appearing in 8 complaints (32% of submitted records). Among these NHTSA complaint records, 1 cites a fire. The 2021 Mercedes-Benz E-Class belongs to the 5th Generation (W213) platform.
Factual proportion of owner complaints categorized by automotive subsystem in NHTSA records
8 owner complaints submitted to NHTSA ODI for this subsystem.
6 owner complaints submitted to NHTSA ODI for this subsystem.
6 owner complaints submitted to NHTSA ODI for this subsystem.
4 owner complaints submitted to NHTSA ODI for this subsystem.
Representative defect filings submitted by owners to the NHTSA Office of Defects Investigation
"Engine misfires, lower engine power, and a lit check engine/Malfunction Indicator Lamp. Mercedes-Benz issued an Emission Service Campaign (No. [PHONE REDACTED], internal code 21P1590208) to replace out-of-spec ignition coils on 657 vehicles from model year 2021, including the E-Class. My VIN was..."
"Vehicle: 2021 Mercedes-Benz E350 Sedan (W213) VIN: [XXX] While operating the vehicle, the diagnostic system displayed the fault code P240200 related to the Evaporative Emission Control System (EVAP). The warning message indicated a “positive short circuit” in the fuel vapor leak diagnosis pump..."
"With the car only have about 15,000 miles the transmission has failed . I have seen there have been recalls of other models with similar complaints of transmission failure ."
"Engine keeps having a misfire that Mercedes put a TSB out for and once the misfire happen I cause the vehicle to go in a limp mode which causes the vehicle to loose power happened to me in the freeway. The car had 54K miles and Mercedes refused to repair the issue as the engine part failure isn’t..."
"My 2021 Mercedes-Benz E350 (VIN [XXX] ) developed a serious engine issue involving cylinder misfire and check engine light. The dealer diagnosed it as a leaking exhaust valve on cylinder 4, related to TSB LI01.30-P-072328, which documents valve seat wear in M260 engines. This is a known defect..."
Reported defect complaint volume across sibling model years (2015–2026)
| Model Year | NHTSA Complaints | Crash Reports | Safety Recalls | Detailed Report |
|---|---|---|---|---|
| 2015 Mercedes-Benz E-Class | 57 | 5 | 6 | View 2015 Problems → |
| 2016 Mercedes-Benz E-Class | 89 | 6 | 5 | View 2016 Problems → |
| 2017 Mercedes-Benz E-Class | 166 | 3 | 20 | View 2017 Problems → |
| 2018 Mercedes-Benz E-Class | 66 | 2 | 6 | View 2018 Problems → |
| 2019 Mercedes-Benz E-Class | 54 | 4 | 20 | View 2019 Problems → |
| 2020 Mercedes-Benz E-Class | 20 | 0 | 14 | View 2020 Problems → |
| 2021 Mercedes-Benz E-Class Current Page | 25 | 0 | 18 | Current |
| 2022 Mercedes-Benz E-Class | 21 | 2 | 8 | View 2022 Problems → |
| 2023 Mercedes-Benz E-Class | 24 | 0 | 5 | View 2023 Problems → |
| 2024 Mercedes-Benz E-Class | 25 | 3 | 0 | View 2024 Problems → |
| 2025 Mercedes-Benz E-Class | 2 | 0 | 2 | View 2025 Problems → |
| 2026 Mercedes-Benz E-Class | 0 | 0 | 0 | View 2026 Problems → |
Complete distribution of consumer defect reports across all 16 granular NHTSA system and subsystem classifications
| Vehicle Component / System | Total Complaints | Crash Reports | Fire Reports | Injury Entries | Fatality Entries |
|---|---|---|---|---|---|
| Engine NHTSA category: ENGINE | 3 | 0 | 0 | 0 | 0 |
| Powertrain NHTSA category: POWER TRAIN | 3 | 0 | 0 | 0 | 0 |
| Other / Uncategorized NHTSA category: UNKNOWN OR OTHER | 3 | 0 | 0 | 0 | 0 |
| Back Over Prevention / Camera NHTSA category: BACK OVER PREVENTION | 2 | 0 | 0 | 0 | 0 |
| Electrical System NHTSA category: ELECTRICAL SYSTEM | 2 | 0 | 0 | 0 | 0 |
| ELECTRICAL SYSTEM,ENGINE | 2 | 0 | 1 | 0 | 0 |
| ELECTRICAL SYSTEM,BACK OVER PREVENTION | 1 | 0 | 0 | 0 | 0 |
| ELECTRICAL SYSTEM,ENGINE,FUEL/PROPULSION SYSTEM | 1 | 0 | 0 | 0 | 0 |
| ELECTRICAL SYSTEM,FUEL/PROPULSION SYSTEM | 1 | 0 | 0 | 0 | 0 |
| Forward Collision Avoidance NHTSA category: FORWARD COLLISION AVOIDANCE | 1 | 0 | 0 | 0 | 0 |
| Fuel System NHTSA category: FUEL SYSTEM, GASOLINE | 1 | 0 | 0 | 0 | 0 |
| POWER TRAIN,ELECTRICAL SYSTEM,ENGINE | 1 | 0 | 0 | 0 | 0 |
| SEAT BELTS,FORWARD COLLISION AVOIDANCE | 1 | 0 | 0 | 0 | 0 |
| Service Brakes NHTSA category: SERVICE BRAKES | 1 | 0 | 0 | 0 | 0 |
| UNKNOWN OR OTHER,BACK OVER PREVENTION | 1 | 0 | 0 | 0 | 0 |
| Wheels & Hubs NHTSA category: WHEELS | 1 | 0 | 0 | 0 | 0 |
Cross-reference safety recalls, crash test safety ratings, and EPA fuel economy for this model year
Key performance indicators, EPA fuel economy specs, powertrain variants, and summary ratings.
Official recall campaigns, safety defect descriptions, and manufacturer free remedy instructions.
NHTSA 5-Star NCAP crash test results, driver assistance systems, and rollover resistance ratings.
EPA fuel economy ratings, electric range, and annual energy cost benchmarks.
Direct, deterministic answers synthesized from verified United States government databases for the 2021 Mercedes-Benz E-Class
In official NHTSA consumer records, the most frequently cited issue area for the 2021 Mercedes-Benz E-Class is Electrical System, appearing in 8 records (32% of submitted filings).
Secondary reported categories include Engine & Cooling (6) and Driver Assistance & Safety Tech (6).
AutoUtility does not issue subjective reliability scores or commercial ratings. In official United States government records, NHTSA tracks 25 consumer defect complaints and 18 safety recall campaigns for the 2021 Mercedes-Benz E-Class.
Reviewing documented component complaint distributions, recall remedy notices, and active federal investigations provides an objective, evidence-based view of the vehicle's historical safety and defect record.
Among consumer complaint records on file with NHTSA for the 2021 Mercedes-Benz E-Class, 0 filings cite a crash, 1 cite smoke or fire, and 0 report one or more injuries.
Incident entries represent consumer descriptions at the time of submission to federal authorities and do not establish mechanical causation or legal liability.
The complaint records on this page are retrieved directly from the NHTSA Office of Defects Investigation (ODI) public database under 49 CFR Part 576.
Local Production Store Compiled: August 2026 • Deterministic Audited Dataset • Zero Dynamic External API Runtime Latency.