2024 Mercedes-Benz E-Class EPA Fuel Economy Summary

The 2024 Mercedes-Benz E-Class delivers an EPA-certified 22–28 MPG combined (19–24 city / 26–34 highway depending on engine and drivetrain) across 14 configurations. Estimated annual fuel costs range from $800 to $3,450.

Combined MPG
22–28 MPG
55% city / 45% highway weighted
City MPG
19–24 MPG
Stop-and-go urban cycle
Highway MPG
26–34 MPG
Sustained open-highway test
Annual Fuel Cost
$800–3,450
EPA estimate @ 15,000 miles/yr

2024 Mercedes-Benz E-Class Powertrain & Efficiency Comparison

Factual efficiency differences across gasoline, hybrid, plug-in hybrid, and electric variants

Gas-Electric Hybrid

Hybrid (HEV) Trims

22–28 MPG Combined

Annual Fuel Cost: $2,700–$3,450

All-Electric

Battery Electric (BEV)

265–307 mi Range • 96 MPGe

Annual Energy Cost: $800–$3,450 (4 configurations)

Official EPA Fuel Economy Ratings by Configuration (14 Variants)

Laboratory certification test values across engine, transmission, and drivetrain permutations

Configuration / Model Powertrain Drivetrain Transmission City Highway Combined EV Range Annual Fuel Cost CO2 (g/mi)
EQE 350 Plus Electricity Electric (BEV) Rear-Wheel Drive Automatic (A1) 98 MPGe 94 MPGe 96 MPGe 298 mi $800
EQE 350 Plus (SUV) Electricity Electric (BEV) Rear-Wheel Drive Automatic (A1) 99 MPGe 88 MPGe 94 MPGe 307 mi $800
EQE 350 4matic Electricity Electric (BEV) All-Wheel Drive Automatic (A1) 86 MPGe 96 MPGe 90 MPGe 280 mi $850
EQE 350 4matic (SUV) Electricity Electric (BEV) All-Wheel Drive Automatic (A1) 88 MPGe 82 MPGe 85 MPGe 265 mi $900
CLE300 4matic (Coupe) Premium 2L Hybrid All-Wheel Drive Automatic 9-spd 24 MPG 34 MPG 28 MPG $2,700
E350 4matic Premium 2L Hybrid All-Wheel Drive Automatic 9-spd 24 MPG 33 MPG 27 MPG $2,800
CLE300 4matic (Convertible) Premium 2L Hybrid All-Wheel Drive Automatic 9-spd 23 MPG 32 MPG 26 MPG $2,900
CLE450 4matic (Convertible) Premium 3L Hybrid All-Wheel Drive Automatic 9-spd 23 MPG 32 MPG 26 MPG $2,900
CLE450 4matic (Coupe) Premium 3L Hybrid All-Wheel Drive Automatic 9-spd 23 MPG 33 MPG 26 MPG $2,900
E450 4matic Premium 3L Hybrid All-Wheel Drive Automatic 9-spd 22 MPG 31 MPG 25 MPG $3,050
E450 4matic All-Terrain (wagon) Premium 3L Hybrid All-Wheel Drive Automatic 9-spd 22 MPG 31 MPG 25 MPG $3,050
GLE350 Premium 2L Hybrid Rear-Wheel Drive Automatic 9-spd 21 MPG 28 MPG 24 MPG $3,150
GLE350 4matic Premium 2L Hybrid All-Wheel Drive Automatic 9-spd 20 MPG 27 MPG 23 MPG $3,300
GLE450 4matic Premium 3L Hybrid All-Wheel Drive Automatic 9-spd 19 MPG 26 MPG 22 MPG $3,450
EPA Test Methodology: Fuel economy estimates are determined by vehicle manufacturers in accordance with EPA regulations (40 CFR Part 600) and verified by EPA laboratories. Estimates assume 15,000 miles per year of driving (55% city, 45% highway) at prevailing fuel and electricity prices.

Deterministic Fuel Cost & Consumption Benchmarks

Standardized annual energy consumption and operating cost metrics based on 15,000 annual miles

Fuel Cost per 25 Miles

$3.13–$3.98

Based on $3.50 per gallon regular gasoline

Annual Fuel Consumption

536–682 Gallons

Estimated annual energy units needed for 15,000 miles

5-Year Fuel Cost vs Avg Vehicle

Official EPA Benchmark

Compared to the average new vehicle over 5 years

Official US Government Data Provenance

Fuel economy ratings, electric range figures, and energy cost estimates on this page are retrieved directly from the United States Environmental Protection Agency (EPA) and U.S. Department of Energy (FuelEconomy.gov) certified vehicle database.

Local Production Store Compiled: August 2026 • Deterministic Audited Dataset • Zero Dynamic External API Runtime Latency.